| Game Name | System |
|---|
| Space Attack / Head On | MAME |
| Space Attack II (bootleg of Super Invaders) | MAME |
| Space Ball | Atari 800 |
| Space Baller (1987)(International Software Koeln) | Atari ST |
| Space Baller (1987)(International Software Koeln)[a] | Atari ST |
| Space Battle (1982)(R. Charlesworth)[b][ZAP start] [SSD] | BBC Micro |
| Space Battle (1987)(Warwick Allison)[k-file] | Atari 800 |
| Space Battle (2004)(Sunnyboy, Simon)(FW) | Atari ST |
| Space Battle (Entex) | MAME |
| Space Battle (bootleg set 1) | MAME |
| Space Battle (bootleg set 2) | MAME |
| Space Battle Ship Gomorrah | MAME |
| Space Bazooka (Japan) | SNES |
| Space Beagle - Hyper Drive (1985)(Codebusters)[cr][b][k-file] | Atari 800 |
| Space Beam | MAME |
| Space Bird (bootleg) | MAME |
| Space Blaster (19xx)(-)(PD)[k-file] | Atari 800 |
| Space Bomber | Amiga |
| Space Bomber | MAME |
| Space Bomber (ver. B) | MAME |
| Space Bomber 2 | Amiga |
| Space Bomber 3 | Amiga |
| Space Bombs | Atari 800 |
| Space Bowl (1982)(Gamma) | Atari 800 |
| Space Bugger (set 1) | MAME |
| Space Bugger (set 2) | MAME |
| Space Bumpers | Atari 800 |
| Space Bust-A-Move (US)(M5)(Venom) | NDS |
| Space Buster (Qps) (Scorpion 4) (set 1) | MAME |
| Space Buster (Qps) (Scorpion 4) (set 2) | MAME |
| Space Cadet | Atari 800 |
| Space Camp (EU)(M5)(BAHAMUT) | NDS |
| Space Camp (US)(M2)(OneUp) | NDS |
| Space Canyon (AKA Space Cavern) (1983) (Panda) (100) | 2600 |
| Space Cavern - Les guerriers de l'espace (1981) (Apollo - Games by Apollo, Dan Oliver - RCA Video Jeux) (AP-2002) (PAL) | 2600 |
| Space Caverns (1985)(Tynesoft) [SSD] | Electron |
| Space Caverns (1985)(Tynesoft) [UEF] | Electron |
| Space Caverns (1985)(Tynesoft)[SC1 start] [SSD] | BBC Micro |
| Space Caverns (1985)(Tynesoft)[a][SC1 start] [SSD] | BBC Micro |
| Space Caverns (1985)(Tynesoft)[h TSTH][bootfile] [SSD] | BBC Micro |
| Space Channel 5 (Europe) (En,Fr,De,Es,It) | PS2 |
| Space Channel 5 (Europe)(En,Fr,De,Es) | DC |
| Space Channel 5 (Japan) | DC |
| Space Channel 5 (USA) | DC |
| Space Channel 5 - Part 2 (Europe) (En,Fr,De,Es,It) | PS2 |
| Space Channel 5 - Part 2 (Japan) | DC |
| Space Channel 5 - Special Edition (USA) (Disc 1) | PS2 |
| Space Channel 5 - Special Edition (USA) (Disc 2) | PS2 |
| Space Channel 5 - Ulala's Cosmic Attack (E)(Independent) | GBA |
| Space Channel 5 - Ulala's Cosmic Attack (U)(Mode7) | GBA |
| Space Chaser (CV version - set 1) | MAME |
| Space Chaser (Model Racing bootleg) | MAME |
| Space Chaser (set 1) | MAME |
| Space Chaser (set 2) | MAME |
| Space Chaser (set 3) | MAME |
| Space Chaser (set 4) | MAME |
| Space Chimps (E)(XenoPhobia) | NDS |
| Space Chimps (Europe) (En,Fr,De,Es,It) | PS2 |
| Space Chimps (U)(XenoPhobia) | NDS |
| Space City | MAME |
| Space City (19xx)(-)[SP-CITY start] [SSD] | BBC Micro |
| Space City (19xx)(-)[a][SP-CITY start] [SSD] | BBC Micro |
| Space Combat | Atari 800 |
| Space Combat (bootleg of Space Invaders) | MAME |
| Space Command (1984)(Virgin Games) | ZX Spectrum Z80 |
| Space Command (1984)(Virgin Games) | ZX Spectrum (TAP) |
| Space Commanders (1983)(Columbia Data Products) | DOS |
| Space Commanders 2 (1984)(Ajf) | DOS |
| Space Commanders II (1985)(Columbia Data Products) | DOS |
| Space Conflict | Atari 800 |
| Space Conflict II (1984)(Trillium)[k-file] | Atari 800 |
| Space Conquest - A Galactic Odyssey | Amiga |
| Space Cowboy (1983)(Avalon Hill)[Req OSb][BASIC] | Atari 800 |
| Space Cruiser | MAME |
| Space Crusade | Amiga |
| Space Crusade (1992)(Gremlin Graphics)(128k) | ZX Spectrum Z80 |
| Space Crusade (1992)(Gremlin Graphics)(128k)[a] | ZX Spectrum Z80 |
| Space Crusade (1992)(Gremlin Interactive Ltd) | DOS |
| Space Crusade (1992)(Gremlin)(M4)(Disk 1 of 2) | Atari ST |
| Space Crusade (1992)(Gremlin)(M4)(Disk 1 of 2)[cr ICS] | Atari ST |
| Space Crusade (1992)(Gremlin)(M4)(Disk 1 of 2)[cr MCA] | Atari ST |
| Space Crusade (1992)(Gremlin)(M4)(Disk 2 of 2) | Atari ST |
| Space Crusade (F) (1990) | CPC |
| Space Crusade II (1992)(Gremlin)(M4)[cr Replicants] | Atari ST |
| Space Cutter (1988)(Maelstrom Games)[protected] | Atari ST |
| Space Day | Amiga |
| Space Defender (19xx)(Chris Andrew) | ZX Spectrum (TAP) |
| Space Defender (19xx)(Chris Andrews) | ZX Spectrum Z80 |
| Space Demon | MAME |
| Space Dodger | Atari 800 |
| Space Dragon (Moon Cresta bootleg, set 1) | MAME |
| Space Dragon (Moon Cresta bootleg, set 2) | MAME |
| Space Dude (1996)(Evryware) | DOS |
| Space Duel (prototype) | MAME |
| Space Duel (version 1) | MAME |
| Space Duel (version 2) | MAME |
| Space Duel, The (UK) (1990) | CPC |
| Space Dungeon | MAME |
| Space Dungeon (1982)(Taito)[m Glenn][5200] | Atari 800 |
| Space Dungeon (1983) (Atari) | 5200 |
