| Game Name | System |
|---|
| Spectrum (ver 4) | MAME |
| Spectrum 2000 (horizontal, buggy) (Europe) | MAME |
| Spectrum 2000 (vertical) | MAME |
| Spectrum Club (Vivid) (MPU5) | MAME |
| Spectrum ED | MAME |
| Spectrum I+ | MAME |
| Speculator Club (Bwb) (MPU4) | MAME |
| Speech+ | MAME |
| Speed Attack! (Japan) | MAME |
| Speed Ball | MAME |
| Speed Ball - Contest at Neonworld (prototype) | MAME |
| Speed Coin (prototype) | MAME |
| Speed Demon (Vivid) (MPU5) | MAME |
| Speed Drop (Ver. 1.06) | MAME |
| Speed Freak | MAME |
| Speed Racer | MAME |
| Speed Spin | MAME |
| Speed Test | MAME |
| Speed Up (Spanish bootleg of Pole Position) | MAME |
| Speed Up (Version 1.00) | MAME |
| Speed Up (Version 1.20) | MAME |
| Spektr BK-001 | MAME |
| Spektr-001 | MAME |
| Spell Master (Russia) (Atronic) | MAME |
| Spellbound | MAME |
| Spellbound (Ace) (sp.ACE) (set 1) | MAME |
| Spellbound (Ace) (sp.ACE) (set 10) | MAME |
| Spellbound (Ace) (sp.ACE) (set 11) | MAME |
| Spellbound (Ace) (sp.ACE) (set 2) | MAME |
| Spellbound (Ace) (sp.ACE) (set 3) | MAME |
| Spellbound (Ace) (sp.ACE) (set 4) | MAME |
| Spellbound (Ace) (sp.ACE) (set 5) | MAME |
| Spellbound (Ace) (sp.ACE) (set 6) | MAME |
| Spellbound (Ace) (sp.ACE) (set 7) | MAME |
| Spellbound (Ace) (sp.ACE) (set 8) | MAME |
| Spelling B (1978 version) | MAME |
| Spelling B (1979 version) | MAME |
| Spelunker | MAME |
| Spelunker (Japan) | MAME |
| Spelunker II | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 1) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 10) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 11) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 12) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 13) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 2) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 3) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 4) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 5) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 6) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 7) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 8) | MAME |
| Spend Spend Spend (Barcrest) (MPU4) (set 9) | MAME |
| Sphinx (v1) (Electrocoin) | MAME |
| Sphinx (v2) (Electrocoin) (set 1) | MAME |
| Sphinx (v2) (Electrocoin) (set 2) | MAME |
| Sphinx II (Russia) (Atronic) | MAME |
| Spice It Up (Bellfruit) (Scorpion 4) (set 1) | MAME |
| Spice It Up (Bellfruit) (Scorpion 4) (set 2) | MAME |
| Spice It Up (Bellfruit) (Scorpion 4) (set 3) | MAME |
| Spice It Up (Bellfruit) (Scorpion 4) (set 4) | MAME |
| Spice It Up (Bellfruit) (Scorpion 5) (set 1) | MAME |
| Spice It Up (Bellfruit) (Scorpion 5) (set 2) | MAME |
| Spice It Up (Bellfruit) (Scorpion 5) (set 3) | MAME |
| Spice It Up (Bellfruit) (Scorpion 5) (set 4) | MAME |
| Spice It Up (Bellfruit) (Scorpion 5) (set 5) | MAME |
| Spice It Up (Bellfruit) (Scorpion 5) (set 6) | MAME |
| Spice It Up (Konami Endeavour) | MAME |
| Spider | MAME |
| Spider-Man v1.30 (English,French) | MAME |
| Spider-Man v1.30 (English,Italian) | MAME |
| Spider-Man v1.30 (English,Spanish) | MAME |
| Spider-Man v1.30 (German,French) | MAME |
| Spider-Man v1.40 | MAME |
| Spider-Man v1.40 (English,French) | MAME |
| Spider-Man v1.40 (English,Italian) | MAME |
| Spider-Man v1.40 (English,Spanish) | MAME |
| Spider-Man v1.40 (German,French) | MAME |
| Spider-Man v1.42 | MAME |
| Spider-Man v1.60 | MAME |
| Spider-Man v1.60 (English,French) | MAME |
| Spider-Man v1.60 (English,Italian) | MAME |
| Spider-Man v1.60 (English,Spanish) | MAME |
| Spider-Man v1.60 (German,French) | MAME |
| Spider-Man v1.70 | MAME |
| Spider-Man v1.70 (English,French) | MAME |
| Spider-Man v1.70 (English,Italian) | MAME |
| Spider-Man v1.70 (English,Spanish) | MAME |
| Spider-Man v1.70 (German,French) | MAME |
| Spider-Man v1.90 | MAME |
| Spider-Man v1.90 (English,French) | MAME |
| Spider-Man v1.90 (English,Italian) | MAME |
| Spider-Man v1.90 (English,Spanish) | MAME |
| Spider-Man v1.90 (German,French) | MAME |
| Spider-Man v1.92 | MAME |
| Spider-Man v1.92 (English,French) | MAME |
| Spider-Man v1.92 (English,Italian) | MAME |
| Spider-Man v1.92 (English,Spanish) | MAME |
| Spider-Man v1.92 (German,French) | MAME |
| Spider-Man v2.00 | MAME |
