| Game Name | System |
|---|
| SABA Videoplay | MAME |
| SABA Videoplay 2 | MAME |
| SAM Coupe | MAME |
| SAPI-1 ZPS 1 | MAME |
| SAPI-1 ZPS 2 | MAME |
| SAPI-1 ZPS 3 | MAME |
| SAPI-1 ZPS 3 (6845) | MAME |
| SAPI-1 ZPS 3 (terminal) | MAME |
| SAR - Search And Rescue (Japan) | MAME |
| SAR - Search And Rescue (US) | MAME |
| SAR - Search And Rescue (World) | MAME |
| SBC6510 | MAME |
| SC-3000/Super Control Station SF-7000 | MAME |
| SCP-300F | MAME |
| SD Fighters (Korea) | MAME |
| SD Gundam Neo Battling (Japan) | MAME |
| SD Gundam Psycho Salamander no Kyoui | MAME |
| SD Gundam Sangokushi Rainbow Tairiku Senki | MAME |
| SD-1 (21 voice) | MAME |
| SD-1 (32 voice) | MAME |
| SDI - Strategic Defense Initiative (Japan, newer, System 16A, FD1089B 317-0027) | MAME |
| SDI - Strategic Defense Initiative (Japan, old, System 16A, FD1089B 317-0027) | MAME |
| SDI - Strategic Defense Initiative (System 16B, FD1089A 317-0028) | MAME |
| SDI - Strategic Defense Initiative (bootleg, original hardware) | MAME |
| SDI - Strategic Defense Initiative (bootleg, set 1) | MAME |
| SDI - Strategic Defense Initiative (bootleg, set 2) | MAME |
| SDI - Strategic Defense Initiative (bootleg, set 3) | MAME |
| SDI - Strategic Defense Initiative (bootleg, set 4) | MAME |
| SDI - Strategic Defense Initiative (bootleg, set 5) | MAME |
| SDK-80 | MAME |
| SDK-85 | MAME |
| SDK-86 | MAME |
| SEL Z80 Trainer | MAME |
| SF-X | MAME |
| SGCPU (aka TI-99/4P) | MAME |
| SLC-1 | MAME |
| SM 7238 | MAME |
| SM1800 | MAME |
| SMC-777 | MAME |
| SMS-1000 | MAME |
| SNK vs. Capcom - SVC Chaos (JAMMA PCB, set 1) | MAME |
| SNK vs. Capcom - SVC Chaos (JAMMA PCB, set 2) | MAME |
| SNK vs. Capcom - SVC Chaos (NGM-2690 ~ NGH-2690) | MAME |
| SNK vs. Capcom - SVC Chaos (bootleg) | MAME |
| SNK vs. Capcom - SVC Chaos Plus (bootleg set 1) | MAME |
| SNK vs. Capcom - SVC Chaos Plus (bootleg set 2) | MAME |
| SNK vs. Capcom - SVC Chaos Super Plus (bootleg) | MAME |
| SOL-20 | MAME |
| SOS | MAME |
| SPARCstation 1 (Sun 4/60) | MAME |
| SPARCstation 1+ (Sun 4/65) | MAME |
| SPARCstation 10 (Sun S10) | MAME |
| SPARCstation 2 (Sun 4/75) | MAME |
| SPARCstation 20 | MAME |
| SPARCstation IPC (Sun 4/40) | MAME |
| SPARCstation IPX (Sun 4/50) | MAME |
| SPARCstation SLC (Sun 4/20) | MAME |
| SPC-1000 | MAME |
| SPC-1500 | MAME |
| SPC-800 (Italy) (MSX1) | MAME |
| SPC-800 (MSX1) | MAME |
| SPT 1500 | MAME |
| SPT 1700 | MAME |
| SPT 1740 | MAME |
| SQ-1 | MAME |
| SQ-2 | MAME |
| SQ-80 | MAME |
| SQ-Rack | MAME |
| SR-16 | MAME |
| SR-16 (Alesis) | MAME |
| SR-16 II | MAME |
| SSI Poker (v2.4) | MAME |
| SSI Poker (v3.0) | MAME |
| SSI Poker (v4.0) | MAME |
| ST (France) | MAME |
| ST (Germany) | MAME |
| ST (Netherlands) | MAME |
| ST (Spain) | MAME |
| ST (Sweden) | MAME |
| ST (Switzerland) | MAME |
| ST (UK) | MAME |
| ST (USA) | MAME |
| ST-1700 (headphone version) | MAME |
| ST-1701 | MAME |
| ST-1702 | MAME |
| ST-1703 | MAME |
| ST-1704 | MAME |
| ST-1705 | MAME |
| ST-1706 | MAME |
| ST-1707 | MAME |
| ST-1708 | MAME |
| ST-1714 | MAME |
| ST-V Bios | MAME |
| STE (France) | MAME |
| STE (Germany) | MAME |
| STE (Italy) | MAME |
| STE (Spain) | MAME |
| STE (Sweden) | MAME |
| STE (Switzerland) | MAME |
| STE (UK) | MAME |
