| Game Name | System |
|---|
| 2096 AD (1991)(Home Data)(Disk 1 of 3)(Disk A) | X68K |
| 2096 AD (1991)(Home Data)(Disk 1 of 3)(Disk A)[a] | X68K |
| 2096 AD (1991)(Home Data)(Disk 2 of 3)(Disk B) | X68K |
| 2096 AD (1991)(Home Data)(Disk 2 of 3)(Disk B)[a] | X68K |
| 2096 AD (1991)(Home Data)(Disk 3 of 3)(Disk C) | X68K |
| 21 (Mirco) | MAME |
| 21 Blackjack | Atari 800 |
| 21 Card Games (Europe) | PS2 |
| 21 Club (Barcrest) [DTW, Dutch] (MPU4) | MAME |
| 21 Emon - Mezase Hotel Ou!! (Japan) | TG16 |
| 21 Two One (Japan) | DC |
| 2112 AD (1985)(Design Design Software) | ZX Spectrum Z80 |
| 2112 AD (1985)(Design Design Software) | ZX Spectrum (TAP) |
| 2112 AD (1985)(Design Design Software)[a2] | ZX Spectrum Z80 |
| 2112 AD (1985)(Design Design Software)[a3] | ZX Spectrum Z80 |
| 2112 AD (1985)(Design Design Software)[a4] | ZX Spectrum Z80 |
| 2112 AD (1985)(Design Design Software)[a5] | ZX Spectrum Z80 |
| 2112 AD (1985)(Design Design Software)[a6] | ZX Spectrum Z80 |
| 2112 AD (1985)(Design Design Software)[a7] | ZX Spectrum Z80 |
| 2112 AD (1985)(Design Design Software)[a8] | ZX Spectrum Z80 |
| 2112 AD (1985)(Design Design Software)[a] | ZX Spectrum Z80 |
| 2112 AD (UK,F) (1986) | CPC |
| 2112 AD (UK,F) (1986) [a1] | CPC |
| 2112 AD (UK,F) (1986) [a2] | CPC |
| 2164 - Hayate no Gotoku! Ojousama Produce Daisakusen Boku Iro ni Somare! Oyashiki-Hen (J)(Navarac) | NDS |
| 2167 - Crayon Shin-Chan - Arashi o Yobu Cinema Land - Kachinko Gachinko Daikatsugeki! (J)(Caravan) | NDS |
| 2182 - Hayate no Gotoku! Ojousama Produce Daisakusen Boku Iro ni Somare! Gakkou-Hen (J)(Independent) | NDS |
| 21st Century Demo (19xx) (PD) | CPC |
| 22 Liubownyje Pozicii (1989)(-)(Ru) | ZX Spectrum (TAP) |
| 221 B Baker St (1986)(Datasoft Inc) | DOS |
| 2217 - Sankei Sports Kanshuu - Wi-Fi Baken Yosou Ryoku Training - Umania 2007 Nendo-ban (J)(Independent) | NDS |
| 221B Baker Street (1987)(Datasoft)[cr 42-Crew] | Atari ST |
| 221B Baker Street (1987)(Datasoft)[cr A-HA] | Atari ST |
| 221B Baker Street (UE) | C64 PP |
| 221B_Baker_Street | Atari 800 |
| 221b Baker Street (1986)(Datasoft)[cr](Disk 1 of 1 Side A) | Apple2 |
| 221b Baker Street (1986)(Datasoft)[cr](Disk 1 of 1 Side B) | Apple2 |
| 22vp931 | MAME |
| 235 U (1992)(L.K. Avalon)(pl)[cr Mr. Bacardi][k-file] | Atari 800 |
| 24 - The Game (Australia) (En,Fr,De,Es,It,Nl,Pl,Hu,Cs) | PS2 |
| 24 - The Game (Europe) (En,Fr,De,Es,It,Nl,Pl,Hu,Cs) | PS2 |
| 24 - The Game (USA) (En,Fr,Es) | PS2 |
| 24 v1.30 | MAME |
| 24 v1.40 | MAME |
| 24 v1.44 | MAME |
| 24 v1.50 | MAME |
| 2400 A.D. (1987)(Chuckles - Origin)(Blank Player Disk) | Apple2 |
| 2400 A.D. (1987)(Chuckles - Origin)(Disk 1 of 2) | Apple2 |
| 2400 A.D. (1987)(Chuckles - Origin)(Disk 2 of 2)(Player) | Apple2 |
| 2400 Ad (1987)(Origin Systems Inc) | DOS |
| 2429 - Simple DS Series Vol. 37 - ALC de Mi ni Tsuku! TOEIC Test - Listening Kyouka Hen (J)(Mishito) | NDS |
| 25 Carrot Gold (Maygay) (EPOCH) (1.1, set 2) | MAME |
| 25 Carrot Gold (Maygay) (EPOCH) (1.2, set 1) | MAME |
| 25 Carrot Gold (Maygay) (EPOCH) (3.1, set 3) | MAME |
| 25 Carrot Gold (Maygay) (EPOCH) (4.1, set 4) | MAME |
| 25 Carrot Gold (Maygay) (EPOCH) (5.1, set 5) | MAME |
| 25 to Life (Europe) | PS2 |
| 25 to Life (USA) | PS2 |
| 250 CC | MAME |
| 2683 - LonQ! Highland in DS - Pu Pu Seijin Arawaru!! - Shukketsu Dai Service! Onara no Saiten SP (J)(Caravan) | NDS |
| 28 Plays Later (Qps) (Scorpion 5) (set 1) | MAME |
| 28 Plays Later (Qps) (Scorpion 5) (set 2) | MAME |
| 280-ZZZAP | MAME |
| 286i | MAME |
| 2999 Nen no Game Kids (J) | PSX |
| 2D House of Terror (World) [English Translated] | DC |
| 2D House of Terror (World) [Español Translated] | DC |
| 2D Mini Maze (1996)(Mark Green) | ZX Spectrum Z80 |
| 2DO Arukotowa Sandoahru (J) | Saturn |
| 2K Sports - The Bigs 2 (US)(BAHAMUT) | NDS |
| 2Xtreme (E) | PSX |
| 2Xtreme (USA) | PSX2PSP |
| 2Xtreme [U] | PSX |
| 2in1 - Best Of Bibi Blocksberg - Neustadt im Hex-Chaos & Das Gestohlene Hexbuch (DE) | NDS |
| 2nd Arukotoha Sando-R (J) | Saturn |
| 2p Nudger (Mdm?) (MPU4) | MAME |
| 2p Unlimited (Mdm) (MPU4) | MAME |
| 3 Bags Full (3VXFC5345, New Zealand) | MAME |
| 3 Bags Full (5VXFC790, Victoria) | MAME |
| 3 Choume no Tama - Tama and Friends - 3 Choume Obake Panic!! (Japan) | GB |
| 3 Count Bout (1995)(SNK)(Jp)[!][Fire Suplex] | NeoGeo CD |
| 3 Count Bout / Fire Suplex | NeoGeo |
| 3 Count Bout / Fire Suplex (NGM-043 ~ NGH-043) | MAME |
| 3 Danhenkei Meka Fuzzy (19xx)(Login)(Disk 1 of 2) | X68K |
| 3 Danhenkei Meka Fuzzy (19xx)(Login)(Disk 2 of 2) | X68K |
| 3 Deep Space (1984)(Postern) | ZX Spectrum Z80 |
| 3 Deep Space (1984)(Postern)[a2] | ZX Spectrum Z80 |
| 3 Deep Space (1984)(Postern)[a] | ZX Spectrum Z80 |
| 3 Demon (1983)(Pc Research) | DOS |
| 3 Guerra Mundial (S) (1989) (Disk 1 of 2) | CPC |
| 3 Guerra Mundial (S) (1989) (Disk 2 of 2) | CPC |
| 3 In 1 College & Pro Football (1984)(Lance Haffner) | Apple2 |
| 3 Jigen Kakutou Ballz (Japan) | SNES |
| 3 Lil' Pigs | MAME |
| 3 Meekaa (1994)(Youkan Soft) | X68K |
| 3 Mega-Tunes (19xx)(Richard Braithwaite)(128k) | ZX Spectrum (TAP) |
| 3 Ninjas Kick Back (U) | SegaCD |
| 3 Ninjas Kick Back (USA) | SNES |
| 3 Ninjas Kick Back (USA) | Genesis |
| 3 On 3 Dunk Madness (US, prototype? 1997/02/04) | MAME |
